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Genome wide transcriptome profiling of a murine acute melioidosis model reveals new insights into how Burkholderia pseudomallei overcomes host innate immunity

Overview of attention for article published in BMC Genomics, November 2010
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Citations

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86 Mendeley
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Title
Genome wide transcriptome profiling of a murine acute melioidosis model reveals new insights into how Burkholderia pseudomallei overcomes host innate immunity
Published in
BMC Genomics, November 2010
DOI 10.1186/1471-2164-11-672
Pubmed ID
Authors

Chui-Yoke Chin, Denise M Monack, Sheila Nathan

Abstract

At present, very little is known about how Burkholderia pseudomallei (B. pseudomallei) interacts with its host to elicit melioidosis symptoms. We established a murine acute-phase melioidosis model and used DNA microarray technology to investigate the global host/pathogen interaction. We compared the transcriptome of infected liver and spleen with uninfected tissues over an infection period of 42 hr to identify genes whose expression is altered in response to an acute infection.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 86 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Thailand 2 2%
France 1 1%
United States 1 1%
Unknown 82 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 30 35%
Student > Master 11 13%
Student > Bachelor 9 10%
Researcher 9 10%
Other 4 5%
Other 11 13%
Unknown 12 14%
Readers by discipline Count As %
Agricultural and Biological Sciences 34 40%
Biochemistry, Genetics and Molecular Biology 14 16%
Immunology and Microbiology 12 14%
Medicine and Dentistry 3 3%
Veterinary Science and Veterinary Medicine 2 2%
Other 7 8%
Unknown 14 16%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 January 2011.
All research outputs
#16,196,698
of 23,879,989 outputs
Outputs from BMC Genomics
#6,888
of 10,855 outputs
Outputs of similar age
#146,336
of 186,100 outputs
Outputs of similar age from BMC Genomics
#61
of 84 outputs
Altmetric has tracked 23,879,989 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 10,855 research outputs from this source. They receive a mean Attention Score of 4.8. This one is in the 27th percentile – i.e., 27% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 186,100 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 11th percentile – i.e., 11% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 84 others from the same source and published within six weeks on either side of this one. This one is in the 22nd percentile – i.e., 22% of its contemporaries scored the same or lower than it.