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Estrogen receptor transcription and transactivation Structure-function relationship in DNA- and ligand-binding domains of estrogen receptors

Overview of attention for article published in Breast Cancer Research, October 2000
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Mentioned by

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2 patents

Citations

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111 Dimensions

Readers on

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86 Mendeley
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Title
Estrogen receptor transcription and transactivation Structure-function relationship in DNA- and ligand-binding domains of estrogen receptors
Published in
Breast Cancer Research, October 2000
DOI 10.1186/bcr80
Pubmed ID
Authors

Marc Ruff, Monique Gangloff, Jean Marie Wurtz, Dino Moras

Abstract

Estrogen receptors are members of the nuclear receptor steroid family that exhibit specific structural features, ligand-binding domain sequence identity and dimeric interactions, that single them out. The crystal structures of their DNA-binding domains give some insight into how nuclear receptors discriminate between DNA response elements. The various ligand-binding domain crystal structures of the two known estrogen receptor isotypes (alpha and beta) allow one to interpret ligand specificity and reveal the interactions responsible for stabilizing the activation helix H12 in the agonist and antagonist positions.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 86 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 86 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 4 5%
Student > Bachelor 3 3%
Student > Ph. D. Student 3 3%
Researcher 2 2%
Student > Postgraduate 2 2%
Other 2 2%
Unknown 70 81%
Readers by discipline Count As %
Agricultural and Biological Sciences 5 6%
Biochemistry, Genetics and Molecular Biology 4 5%
Medicine and Dentistry 2 2%
Pharmacology, Toxicology and Pharmaceutical Science 1 1%
Immunology and Microbiology 1 1%
Other 3 3%
Unknown 70 81%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 May 2018.
All research outputs
#8,534,528
of 25,371,288 outputs
Outputs from Breast Cancer Research
#977
of 2,052 outputs
Outputs of similar age
#13,181
of 38,859 outputs
Outputs of similar age from Breast Cancer Research
#1
of 3 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,052 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.2. This one is in the 39th percentile – i.e., 39% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 38,859 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 10th percentile – i.e., 10% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 3 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them