Title |
B Lymphocyte intestinal homing in inflammatory bowel disease
|
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Published in |
BMC Immunology, December 2011
|
DOI | 10.1186/1471-2172-12-71 |
Pubmed ID | |
Authors |
Caterina Defendenti, Piercarlo Sarzi-Puttini, Silvia Grosso, Annamaria Croce, Olivia Senesi, Simone Saibeni, Simona Bollani, Piero Luigi Almasio, Savino Bruno, Fabiola Atzeni |
Abstract |
Inflammatory bowel disease (IBD) is thought to be due to an abnormal interaction between the host immune system and commensal microflora. Within the intestinal immune system, B cells produce physiologically natural antibodies but pathologically atypical anti-neutrophil antibodies (xANCAs) are frequently observed in patients with IBD. The objective is to investigate the localisation of immunoglobulin-producing cells (IPCs) in samples of inflamed intestinal tissue taken from patients with IBD, and their possible relationship with clinical features. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United Kingdom | 1 | 33% |
Unknown | 2 | 67% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 3 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Denmark | 1 | 2% |
Unknown | 53 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 12 | 22% |
Student > Master | 8 | 15% |
Student > Bachelor | 7 | 13% |
Student > Ph. D. Student | 6 | 11% |
Student > Doctoral Student | 3 | 6% |
Other | 7 | 13% |
Unknown | 11 | 20% |
Readers by discipline | Count | As % |
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Agricultural and Biological Sciences | 15 | 28% |
Medicine and Dentistry | 11 | 20% |
Biochemistry, Genetics and Molecular Biology | 4 | 7% |
Immunology and Microbiology | 4 | 7% |
Computer Science | 2 | 4% |
Other | 2 | 4% |
Unknown | 16 | 30% |