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X Demographics
Mendeley readers
Attention Score in Context
| Title |
HIF-1 activation induces doxorubicin resistance in MCF7 3-D spheroids via P-glycoprotein expression: a potential model of the chemo-resistance of invasive micropapillary carcinoma of the breast
|
|---|---|
| Published in |
BMC Cancer, January 2012
|
| DOI | 10.1186/1471-2407-12-4 |
| Pubmed ID | |
| Authors |
Sophie Doublier, Dimas C Belisario, Manuela Polimeni, Laura Annaratone, Chiara Riganti, Elena Allia, Dario Ghigo, Amalia Bosia, Anna Sapino |
| Abstract |
Invasive micropapillary carcinoma (IMPC) of the breast is a distinct and aggressive variant of luminal type B breast cancer that does not respond to neoadjuvant chemotherapy. It is characterized by small pseudopapillary clusters of cancer cells with inverted cell polarity. To investigate whether hypoxia-inducible factor-1 (HIF-1) activation may be related to the drug resistance described in this tumor, we used MCF7 cancer cells cultured as 3-D spheroids, which morphologically simulate IMPC cell clusters. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 2 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Practitioners (doctors, other healthcare professionals) | 1 | 50% |
| Members of the public | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 138 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Hungary | 1 | <1% |
| Turkey | 1 | <1% |
| Indonesia | 1 | <1% |
| Austria | 1 | <1% |
| Argentina | 1 | <1% |
| Unknown | 133 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 36 | 26% |
| Researcher | 18 | 13% |
| Student > Master | 18 | 13% |
| Student > Bachelor | 15 | 11% |
| Student > Doctoral Student | 7 | 5% |
| Other | 15 | 11% |
| Unknown | 29 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 30 | 22% |
| Agricultural and Biological Sciences | 29 | 21% |
| Medicine and Dentistry | 24 | 17% |
| Engineering | 5 | 4% |
| Chemistry | 4 | 3% |
| Other | 12 | 9% |
| Unknown | 34 | 25% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 January 2015.
All research outputs
#6,377,904
of 22,661,413 outputs
Outputs from BMC Cancer
#1,625
of 8,239 outputs
Outputs of similar age
#57,708
of 244,244 outputs
Outputs of similar age from BMC Cancer
#16
of 87 outputs
Altmetric has tracked 22,661,413 research outputs across all sources so far. This one has received more attention than most of these and is in the 70th percentile.
So far Altmetric has tracked 8,239 research outputs from this source. They receive a mean Attention Score of 4.3. This one has done well, scoring higher than 79% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 244,244 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 74% of its contemporaries.
We're also able to compare this research output to 87 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 81% of its contemporaries.