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X Demographics
Mendeley readers
Attention Score in Context
| Title |
The new pLAI (lux regulon based auto-inducible) expression system for recombinant protein production in Escherichia coli
|
|---|---|
| Published in |
Microbial Cell Factories, January 2012
|
| DOI | 10.1186/1475-2859-11-3 |
| Pubmed ID | |
| Authors |
Salvatore Nocadello, Erwin Frans Swennen |
| Abstract |
After many years of intensive research, it is generally assumed that no universal expression system can exist for high-level production of a given recombinant protein. Among the different expression systems, the inducible systems are the most popular for their tight regulation. However, induction is in many cases less favorable due to the high cost and/or toxicity of inducers, incompatibilities with industrial scale-up or detrimental growth conditions. Expression systems using autoinduction (or self-induction) prove to be extremely versatile allowing growth and induction of recombinant proteins without the need to monitor cell density or add inducer. Unfortunately, almost all the actual auto inducible expression systems need endogenous or induced metabolic changes during the growth to trigger induction, both frequently linked to detrimental condition to cell growth. In this context, we use a simple modular approach for a cell density-based genetic regulation in order to assemble an autoinducible recombinant protein expression system in E. coli. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 86 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 2 | 2% |
| United Kingdom | 1 | 1% |
| Canada | 1 | 1% |
| Unknown | 82 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 18 | 21% |
| Researcher | 16 | 19% |
| Student > Bachelor | 14 | 16% |
| Student > Master | 9 | 10% |
| Student > Doctoral Student | 3 | 3% |
| Other | 8 | 9% |
| Unknown | 18 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 28 | 33% |
| Biochemistry, Genetics and Molecular Biology | 19 | 22% |
| Engineering | 6 | 7% |
| Chemistry | 6 | 7% |
| Medicine and Dentistry | 2 | 2% |
| Other | 5 | 6% |
| Unknown | 20 | 23% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 December 2013.
All research outputs
#7,960,052
of 25,374,647 outputs
Outputs from Microbial Cell Factories
#547
of 1,823 outputs
Outputs of similar age
#66,627
of 249,144 outputs
Outputs of similar age from Microbial Cell Factories
#9
of 24 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one has received more attention than most of these and is in the 67th percentile.
So far Altmetric has tracked 1,823 research outputs from this source. They receive a mean Attention Score of 4.9. This one has gotten more attention than average, scoring higher than 69% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 249,144 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.
We're also able to compare this research output to 24 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 58% of its contemporaries.