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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Ubiquitin carboxyl-terminal hydrolase 1 (UCHL1) is a potential tumour suppressor in prostate cancer and is frequently silenced by promoter methylation
|
|---|---|
| Published in |
Molecular Cancer, October 2011
|
| DOI | 10.1186/1476-4598-10-129 |
| Pubmed ID | |
| Authors |
Ramesh Ummanni, Edgar Jost, Melanie Braig, Frithjof Lohmann, Frederike Mundt, Christine Barett, Thorsten Schlomm, Guido Sauter, Tina Senff, Carsten Bokemeyer, Holger Sültmann, Catherine Meyer-Schwesinger, Tim H Brümmendorf, Stefan Balabanov |
| Abstract |
We have previously reported significant downregulation of ubiquitin carboxyl-terminal hydrolase 1 (UCHL1) in prostate cancer (PCa) compared to the surrounding benign tissue. UCHL1 plays an important role in ubiquitin system and different cellular processes such as cell proliferation and differentiation. We now show that the underlying mechanism of UCHL1 downregulation in PCa is linked to its promoter hypermethylation. Furthermore, we present evidences that UCHL1 expression can affect the behavior of prostate cancer cells in different ways. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 54 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| South Africa | 1 | 2% |
| Unknown | 53 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 18 | 33% |
| Researcher | 13 | 24% |
| Student > Bachelor | 4 | 7% |
| Student > Master | 4 | 7% |
| Student > Postgraduate | 3 | 6% |
| Other | 9 | 17% |
| Unknown | 3 | 6% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 19 | 35% |
| Medicine and Dentistry | 10 | 19% |
| Biochemistry, Genetics and Molecular Biology | 10 | 19% |
| Chemistry | 8 | 15% |
| Environmental Science | 2 | 4% |
| Other | 1 | 2% |
| Unknown | 4 | 7% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 February 2014.
All research outputs
#14,597,188
of 22,661,413 outputs
Outputs from Molecular Cancer
#964
of 1,713 outputs
Outputs of similar age
#91,733
of 136,373 outputs
Outputs of similar age from Molecular Cancer
#13
of 15 outputs
Altmetric has tracked 22,661,413 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,713 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one is in the 43rd percentile – i.e., 43% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 136,373 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 32nd percentile – i.e., 32% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 15 others from the same source and published within six weeks on either side of this one. This one is in the 6th percentile – i.e., 6% of its contemporaries scored the same or lower than it.