You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output.
Click here to find out more.
X Demographics
Mendeley readers
Attention Score in Context
| Title |
Hyaluronidase: from clinical applications to molecular and cellular mechanisms
|
|---|---|
| Published in |
European Journal of Medical Research, February 2016
|
| DOI | 10.1186/s40001-016-0201-5 |
| Pubmed ID | |
| Authors |
Bettina Alexandra Buhren, Holger Schrumpf, Norman-Philipp Hoff, Edwin Bölke, Said Hilton, Peter Arne Gerber |
| Abstract |
Over the past 60 years, hyaluronidase has been successfully utilized in ophthalmic surgery and is now being implemented in dermatosurgery as well as in other surgical disciplines. The enzyme is considered a "spreading factor" as it decomplexes hyaluronic acid (also called hyaluronan, HA), an essential component of the extracellular matrix (ECM). When applied as an adjuvant, hyaluronidase enhances the diffusion capacity and bioavailability of injected drugs. Therefore, the enzyme has been used as a local adjuvant to increase the diffusion capacity of local anesthetics, increasing the analgesic efficacy, and the anesthetized area particularly in the first minutes following injection, resulting in diminished intra- and postoperative pain. In aesthetic medicine, the off-label use of hyaluronidase is considered the gold standard for the management of HA-filler-associated complications. Here, we review the clinical use, underlying biological mechanisms, and future directions for the application of hyaluronidase in surgical and aesthetic medicine. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 2 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 288 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 2 | <1% |
| France | 1 | <1% |
| Unknown | 285 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 43 | 15% |
| Student > Bachelor | 38 | 13% |
| Student > Master | 29 | 10% |
| Researcher | 28 | 10% |
| Student > Postgraduate | 13 | 5% |
| Other | 50 | 17% |
| Unknown | 87 | 30% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 55 | 19% |
| Biochemistry, Genetics and Molecular Biology | 37 | 13% |
| Agricultural and Biological Sciences | 25 | 9% |
| Pharmacology, Toxicology and Pharmaceutical Science | 18 | 6% |
| Chemistry | 18 | 6% |
| Other | 39 | 14% |
| Unknown | 96 | 33% |
Attention Score in Context
This research output has an Altmetric Attention Score of 37. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 January 2023.
All research outputs
#1,090,978
of 25,373,627 outputs
Outputs from European Journal of Medical Research
#31
of 923 outputs
Outputs of similar age
#20,129
of 410,079 outputs
Outputs of similar age from European Journal of Medical Research
#2
of 6 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 95th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 923 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.8. This one has done particularly well, scoring higher than 96% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 410,079 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 6 others from the same source and published within six weeks on either side of this one. This one has scored higher than 4 of them.