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Efficient in vitro RNA interference and immunofluorescence-based phenotype analysis in a human parasitic nematode, Brugia malayi

Overview of attention for article published in Parasites & Vectors, January 2012
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Title
Efficient in vitro RNA interference and immunofluorescence-based phenotype analysis in a human parasitic nematode, Brugia malayi
Published in
Parasites & Vectors, January 2012
DOI 10.1186/1756-3305-5-16
Pubmed ID
Authors

Frédéric Landmann, Jeremy M Foster, Barton E Slatko, William Sullivan

Abstract

RNA interference (RNAi) is an efficient reverse genetics technique for investigating gene function in eukaryotes. The method has been widely used in model organisms, such as the free-living nematode Caenorhabditis elegans, where it has been deployed in genome-wide high throughput screens to identify genes involved in many cellular and developmental processes. However, RNAi techniques have not translated efficiently to animal parasitic nematodes that afflict humans, livestock and companion animals across the globe, creating a dependency on data tentatively inferred from C. elegans.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 45 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Indonesia 1 2%
Unknown 44 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 11 24%
Researcher 8 18%
Student > Master 6 13%
Professor > Associate Professor 5 11%
Student > Doctoral Student 4 9%
Other 8 18%
Unknown 3 7%
Readers by discipline Count As %
Agricultural and Biological Sciences 23 51%
Biochemistry, Genetics and Molecular Biology 13 29%
Immunology and Microbiology 2 4%
Nursing and Health Professions 1 2%
Medicine and Dentistry 1 2%
Other 1 2%
Unknown 4 9%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 January 2012.
All research outputs
#15,241,259
of 22,661,413 outputs
Outputs from Parasites & Vectors
#3,351
of 5,427 outputs
Outputs of similar age
#161,787
of 243,250 outputs
Outputs of similar age from Parasites & Vectors
#31
of 37 outputs
Altmetric has tracked 22,661,413 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 5,427 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one is in the 30th percentile – i.e., 30% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 243,250 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 22nd percentile – i.e., 22% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 37 others from the same source and published within six weeks on either side of this one. This one is in the 16th percentile – i.e., 16% of its contemporaries scored the same or lower than it.