Title |
Treatment of imported severe malaria with artesunate instead of quinine - more evidence needed?
|
---|---|
Published in |
Malaria Journal, September 2011
|
DOI | 10.1186/1475-2875-10-256 |
Pubmed ID | |
Authors |
Jakob P Cramer, Rogelio López-Vélez, Gerd D Burchard, Martin P Grobusch, Peter J de Vries |
Abstract |
Rapid and fast acting anti-malarials are essential to treat severe malaria. Quinine has been the only option for parenteral therapy until recently. While current evidence shows that intravenous artesunate is more effective than quinine in treating severe malaria in endemic countries, some questions remain regarding safety profiles and drug resistance. For imported severe malaria, additional unanswered questions are related to generalizability of the findings from endemic countries and to legal aspects, as there is no Good Manufacturing Practice-conform drug available yet. Here, the implications of existing evidence for the treatment of imported severe malaria are discussed. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 3 | 7% |
Germany | 1 | 2% |
Portugal | 1 | 2% |
India | 1 | 2% |
Pakistan | 1 | 2% |
Unknown | 39 | 85% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Other | 7 | 15% |
Student > Bachelor | 7 | 15% |
Researcher | 6 | 13% |
Student > Doctoral Student | 5 | 11% |
Student > Ph. D. Student | 5 | 11% |
Other | 13 | 28% |
Unknown | 3 | 7% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 21 | 46% |
Pharmacology, Toxicology and Pharmaceutical Science | 8 | 17% |
Nursing and Health Professions | 3 | 7% |
Agricultural and Biological Sciences | 3 | 7% |
Biochemistry, Genetics and Molecular Biology | 2 | 4% |
Other | 3 | 7% |
Unknown | 6 | 13% |