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CCR6 is not necessary for functional effects of human CCL18 in a mouse model

Overview of attention for article published in Fibrogenesis & Tissue Repair, January 2012
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (83rd percentile)

Mentioned by

blogs
1 blog

Citations

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9 Dimensions

Readers on

mendeley
5 Mendeley
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Title
CCR6 is not necessary for functional effects of human CCL18 in a mouse model
Published in
Fibrogenesis & Tissue Repair, January 2012
DOI 10.1186/1755-1536-5-2
Pubmed ID
Authors

Irina G Luzina, Sergei P Atamas

Abstract

CCL18, a chemokine with no known receptor, has been implicated in several fibrotic pulmonary diseases associated with T-lymphocyte infiltration. It has been hypothesized that CCL18 may act through CCR6. Gene delivery of human CCL18 to the lungs of wild-type mice induced pulmonary infiltration of T-lymphocytes, less than 5% of which expressed CCR6. In the lungs of CCR6-deficient mice, CCL18-driven infiltration of T-lymphocytes was attenuated but not fully abrogated. It was concluded that CCR6 is not necessary for CCL18-induced changes in mice in vivo and that CCR6 is not the main functional receptor for CCL18 in this model.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 5 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 5 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 2 40%
Unspecified 1 20%
Student > Doctoral Student 1 20%
Unknown 1 20%
Readers by discipline Count As %
Unspecified 1 20%
Biochemistry, Genetics and Molecular Biology 1 20%
Immunology and Microbiology 1 20%
Medicine and Dentistry 1 20%
Unknown 1 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 January 2012.
All research outputs
#4,644,468
of 22,661,413 outputs
Outputs from Fibrogenesis & Tissue Repair
#20
of 83 outputs
Outputs of similar age
#41,375
of 245,904 outputs
Outputs of similar age from Fibrogenesis & Tissue Repair
#1
of 2 outputs
Altmetric has tracked 22,661,413 research outputs across all sources so far. Compared to these this one has done well and is in the 79th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 83 research outputs from this source. They receive a mean Attention Score of 4.4. This one has done well, scoring higher than 75% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 245,904 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 83% of its contemporaries.
We're also able to compare this research output to 2 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them