Title |
Endothelial progenitor cells and burn injury – exploring the relationship
|
---|---|
Published in |
Burns & Trauma, February 2016
|
DOI | 10.1186/s41038-016-0028-x |
Pubmed ID | |
Authors |
Derek A. Banyard, Blake O. Adnani, Satenik Melkumyan, Cheryl Ann Araniego, Alan D. Widgerow |
Abstract |
Burn wounds result in varying degrees of soft tissue damage that are typically graded clinically. Recently a key participant in neovascularization, the endothelial progenitor cell, has been the subject of intense cardiovascular research to explore whether it can serve as a biomarker for vascular injury. In this review, we examine the identity of the endothelial progenitor cell as well as the evidence that support its role as a key responder after burn insult. While there is conflicting evidence with regards to the delta of endothelial progenitor cell mobilization and burn severity, it is clear that they play an important role in wound healing. Systematic and controlled studies are needed to clarify this relationship, and whether this population can serve as a biomarker for burn severity. |
X Demographics
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Scientists | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United States | 1 | 8% |
Unknown | 11 | 92% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 3 | 25% |
Professor > Associate Professor | 2 | 17% |
Student > Doctoral Student | 1 | 8% |
Student > Bachelor | 1 | 8% |
Lecturer | 1 | 8% |
Other | 4 | 33% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 8 | 67% |
Biochemistry, Genetics and Molecular Biology | 4 | 33% |