Title |
Systematic screening for novel, serologically reactive Hepatitis E Virus epitopes
|
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Published in |
Virology Journal, January 2012
|
DOI | 10.1186/1743-422x-9-28 |
Pubmed ID | |
Authors |
Andreas Osterman, Maria Guadalupe Vizoso Pinto, Rudolf Haase, Hans Nitschko, Simone Jäger, Michaela Sander, Manfred Motz, Ulrich Mohn, Armin Baiker |
Abstract |
The National Institutes of Health classified Hepatitis E as an emerging disease since Hepatitis E Virus (HEV) is the major cause of acute hepatitis in developing countries. Interestingly, an increasing number of sporadic cases of HEV infections are described in industrialized countries as zoonosis from domestic livestock. Despite the increasing relevance of this pathogen in clinical virology, commercial antibody assays are mainly based on fragments of HEV open reading frame (ORF) 2 and ORF3. The largest ORF1 (poly-)protein, however, is not part of current testing formats. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Kenya | 1 | <1% |
Unknown | 165 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 10 | 6% |
Student > Master | 6 | 4% |
Student > Ph. D. Student | 5 | 3% |
Student > Doctoral Student | 3 | 2% |
Other | 2 | 1% |
Other | 6 | 4% |
Unknown | 134 | 81% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 10 | 6% |
Immunology and Microbiology | 5 | 3% |
Medicine and Dentistry | 3 | 2% |
Veterinary Science and Veterinary Medicine | 2 | 1% |
Social Sciences | 2 | 1% |
Other | 7 | 4% |
Unknown | 137 | 83% |