Title |
miRdSNP: a database of disease-associated SNPs and microRNA target sites on 3'UTRs of human genes
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Published in |
BMC Genomics, January 2012
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DOI | 10.1186/1471-2164-13-44 |
Pubmed ID | |
Authors |
Andrew E Bruno, Li Li, James L Kalabus, Yuzhuo Pan, Aiming Yu, Zihua Hu |
Abstract |
Single nucleotide polymorphisms (SNPs) can lead to the susceptibility and onset of diseases through their effects on gene expression at the posttranscriptional level. Recent findings indicate that SNPs could create, destroy, or modify the efficiency of miRNA binding to the 3'UTR of a gene, resulting in gene dysregulation. With the rapidly growing number of published disease-associated SNPs (dSNPs), there is a strong need for resources specifically recording dSNPs on the 3'UTRs and their nucleotide distance from miRNA target sites. We present here miRdSNP, a database incorporating three important areas of dSNPs, miRNA target sites, and diseases. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Germany | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 50% |
Scientists | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Germany | 1 | <1% |
Italy | 1 | <1% |
India | 1 | <1% |
United Kingdom | 1 | <1% |
Denmark | 1 | <1% |
Spain | 1 | <1% |
United States | 1 | <1% |
Poland | 1 | <1% |
Unknown | 107 | 93% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 31 | 27% |
Student > Ph. D. Student | 28 | 24% |
Student > Bachelor | 11 | 10% |
Student > Master | 11 | 10% |
Student > Doctoral Student | 10 | 9% |
Other | 11 | 10% |
Unknown | 13 | 11% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 47 | 41% |
Biochemistry, Genetics and Molecular Biology | 26 | 23% |
Medicine and Dentistry | 9 | 8% |
Computer Science | 5 | 4% |
Neuroscience | 4 | 3% |
Other | 5 | 4% |
Unknown | 19 | 17% |