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p38 MAPK, Microglial Signaling, and Neuropathic Pain

Overview of attention for article published in Molecular Pain, November 2007
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (73rd percentile)

Mentioned by

patent
3 patents

Citations

dimensions_citation
511 Dimensions

Readers on

mendeley
318 Mendeley
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Title
p38 MAPK, Microglial Signaling, and Neuropathic Pain
Published in
Molecular Pain, November 2007
DOI 10.1186/1744-8069-3-33
Pubmed ID
Authors

Ru-Rong Ji, Marc R Suter

Abstract

Accumulating evidence over last several years indicates an important role of microglial cells in the pathogenesis of neuropathic pain. Signal transduction in microglia under chronic pain states has begun to be revealed. We will review the evidence that p38 MAPK is activated in spinal microglia after nerve injury and contributes importantly to neuropathic pain development and maintenance. We will discuss the upstream mechanisms causing p38 activation in spinal microglia after nerve injury. We will also discuss the downstream mechanisms by which p38 produces inflammatory mediators. Taken together, current data suggest that p38 plays a critical role in microglial signaling under neuropathic pain conditions and represents a valuable therapeutic target for neuropathic pain management.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 318 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 6 2%
Spain 3 <1%
Romania 2 <1%
Brazil 1 <1%
United Kingdom 1 <1%
Iran, Islamic Republic of 1 <1%
Australia 1 <1%
Canada 1 <1%
Germany 1 <1%
Other 0 0%
Unknown 301 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 65 20%
Researcher 48 15%
Student > Master 38 12%
Student > Bachelor 29 9%
Student > Doctoral Student 27 8%
Other 59 19%
Unknown 52 16%
Readers by discipline Count As %
Agricultural and Biological Sciences 62 19%
Medicine and Dentistry 59 19%
Neuroscience 54 17%
Pharmacology, Toxicology and Pharmaceutical Science 24 8%
Biochemistry, Genetics and Molecular Biology 18 6%
Other 39 12%
Unknown 62 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 January 2023.
All research outputs
#5,447,195
of 25,374,917 outputs
Outputs from Molecular Pain
#106
of 669 outputs
Outputs of similar age
#16,322
of 89,273 outputs
Outputs of similar age from Molecular Pain
#1
of 4 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done well and is in the 75th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 669 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.1. This one has done well, scoring higher than 82% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 89,273 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 73% of its contemporaries.
We're also able to compare this research output to 4 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them