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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Identification and manipulation of tumor associated macrophages in human cancers
|
|---|---|
| Published in |
Journal of Translational Medicine, December 2011
|
| DOI | 10.1186/1479-5876-9-216 |
| Pubmed ID | |
| Authors |
Moniek Heusinkveld, Sjoerd H van der Burg |
| Abstract |
Evading immune destruction and tumor promoting inflammation are important hallmarks in the development of cancer. Macrophages are present in most human tumors and are often associated with bad prognosis. Tumor associated macrophages come in many functional flavors ranging from what is known as classically activated macrophages (M1) associated with acute inflammation and T-cell immunity to immune suppressive macrophages (M2) associated with the promotion of tumor growth. The role of these functionally different myeloid cells is extensively studied in mice tumor models but dissimilarities in markers and receptors make the direct translation to human cancer difficult. This review focuses on recent reports discriminating the type of infiltrating macrophages in human tumors and the environmental cues present that steer their differentiation. Finally, immunotherapeutic approaches to interfere in this process are discussed. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Grenada | 1 | 50% |
| United States | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 468 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 5 | 1% |
| Germany | 2 | <1% |
| France | 2 | <1% |
| Belgium | 2 | <1% |
| Spain | 2 | <1% |
| India | 1 | <1% |
| United Kingdom | 1 | <1% |
| Denmark | 1 | <1% |
| Brazil | 1 | <1% |
| Other | 2 | <1% |
| Unknown | 449 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 108 | 23% |
| Researcher | 89 | 19% |
| Student > Master | 62 | 13% |
| Student > Bachelor | 49 | 10% |
| Student > Doctoral Student | 26 | 6% |
| Other | 59 | 13% |
| Unknown | 75 | 16% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 116 | 25% |
| Medicine and Dentistry | 110 | 24% |
| Biochemistry, Genetics and Molecular Biology | 57 | 12% |
| Immunology and Microbiology | 34 | 7% |
| Chemistry | 10 | 2% |
| Other | 41 | 9% |
| Unknown | 100 | 21% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 May 2012.
All research outputs
#15,241,801
of 22,662,201 outputs
Outputs from Journal of Translational Medicine
#2,213
of 3,951 outputs
Outputs of similar age
#162,379
of 241,497 outputs
Outputs of similar age from Journal of Translational Medicine
#37
of 60 outputs
Altmetric has tracked 22,662,201 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,951 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.4. This one is in the 31st percentile – i.e., 31% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 241,497 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 21st percentile – i.e., 21% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 60 others from the same source and published within six weeks on either side of this one. This one is in the 33rd percentile – i.e., 33% of its contemporaries scored the same or lower than it.