Title |
Increased liver stiffness denotes hepatic dysfunction and mortality risk in critically ill non-cirrhotic patients at a medical ICU
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Published in |
Critical Care, November 2011
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DOI | 10.1186/cc10543 |
Pubmed ID | |
Authors |
Alexander Koch, Andreas Horn, Hanna Dückers, Eray Yagmur, Edouard Sanson, Jan Bruensing, Lukas Buendgens, Sebastian Voigt, Christian Trautwein, Frank Tacke |
Abstract |
Hepatic dysfunction is a common finding in critically ill patients on the ICU and directly influences survival. Liver stiffness can be measured by the novel method of transient elastography (fibroscan) and is closely associated with hepatic fibrosis in patients with chronic liver disease, but also is increased in patients with acute hepatitis, acute liver failure and cholestasis. We investigated liver stiffness as a potentially useful tool for early detection of patients with hepatic deterioration and risk stratification with respect to short- and long-term mortality. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Italy | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Japan | 1 | 1% |
United States | 1 | 1% |
Canada | 1 | 1% |
Unknown | 71 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 13 | 18% |
Student > Master | 9 | 12% |
Researcher | 8 | 11% |
Student > Doctoral Student | 7 | 9% |
Student > Postgraduate | 7 | 9% |
Other | 18 | 24% |
Unknown | 12 | 16% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 35 | 47% |
Agricultural and Biological Sciences | 5 | 7% |
Engineering | 4 | 5% |
Biochemistry, Genetics and Molecular Biology | 3 | 4% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 3% |
Other | 8 | 11% |
Unknown | 17 | 23% |