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X Demographics
Mendeley readers
Attention Score in Context
| Title |
miR-31 and its host gene lncRNA LOC554202 are regulated by promoter hypermethylation in triple-negative breast cancer
|
|---|---|
| Published in |
Molecular Cancer, January 2012
|
| DOI | 10.1186/1476-4598-11-5 |
| Pubmed ID | |
| Authors |
Katarzyna Augoff, Brian McCue, Edward F Plow, Khalid Sossey-Alaoui |
| Abstract |
microRNAs have been established as powerful regulators of gene expression in normal physiological as well as in pathological conditions, including cancer progression and metastasis. Recent studies have demonstrated a key role of miR-31 in the progression and metastasis of breast cancer. Downregulation of miR-31 enhances several steps of the invasion-metastasis cascade in breast cancer, i.e., local invasion, extravasation and survival in the circulation system, and metastatic colonization of distant sites. miR-31 exerts its metastasis-suppressor activity by targeting a cohort of pro-metastatic genes, including RhoA and WAVE3. The molecular mechanisms that lead to the loss of miR-31 and the activation of its pro-metastatic target genes during these specific steps of the invasion-metastasis cascade are however unknown. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Italy | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 184 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Hungary | 2 | 1% |
| Belgium | 2 | 1% |
| France | 1 | <1% |
| Netherlands | 1 | <1% |
| China | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 176 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 49 | 27% |
| Researcher | 31 | 17% |
| Student > Master | 24 | 13% |
| Student > Bachelor | 14 | 8% |
| Student > Postgraduate | 10 | 5% |
| Other | 24 | 13% |
| Unknown | 32 | 17% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 48 | 26% |
| Biochemistry, Genetics and Molecular Biology | 44 | 24% |
| Medicine and Dentistry | 26 | 14% |
| Engineering | 6 | 3% |
| Immunology and Microbiology | 5 | 3% |
| Other | 22 | 12% |
| Unknown | 33 | 18% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 January 2012.
All research outputs
#18,376,056
of 22,760,687 outputs
Outputs from Molecular Cancer
#1,288
of 1,718 outputs
Outputs of similar age
#197,060
of 247,183 outputs
Outputs of similar age from Molecular Cancer
#8
of 12 outputs
Altmetric has tracked 22,760,687 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,718 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one is in the 14th percentile – i.e., 14% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 247,183 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 9th percentile – i.e., 9% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 12 others from the same source and published within six weeks on either side of this one. This one is in the 16th percentile – i.e., 16% of its contemporaries scored the same or lower than it.