Report for: Single vesicle imaging indicates distinct modes of rapid membrane retrieval during nerve growth

Title	Single vesicle imaging indicates distinct modes of rapid membrane retrieval during nerve growth
Published in	BMC Biology, January 2012
DOI	10.1186/1741-7007-10-4
Pubmed ID	22289422
Authors	Jacob H Hines, Steven J Henle, Lucas P Carlstrom, Mohammad Abu-Rub, John R Henley
Abstract	During nerve growth, cytoplasmic vesicles add new membrane preferentially to the growth cone located at the distal tip of extending axons. Growth cone membrane is also retrieved locally, and asymmetric retrieval facilitates membrane remodeling during growth cone repulsion by a chemorepellent gradient. Moreover, growth inhibitory factors can stimulate bulk membrane retrieval and induce growth cone collapse. Despite these functional insights, the processes mediating local membrane remodeling during axon extension remain poorly defined.

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Unknown	8	19%

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Neuroscience	3	7%
Physics and Astronomy	2	5%
Other	2	5%
Unknown	8	19%

Single vesicle imaging indicates distinct modes of rapid membrane retrieval during nerve growth