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Assessing the joint effect of population stratification and sample selection in studies of gene-gene (environment) interactions

Overview of attention for article published in BMC Genomic Data, January 2012
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (88th percentile)
  • High Attention Score compared to outputs of the same age and source (93rd percentile)

Mentioned by

blogs
1 blog
twitter
6 X users

Citations

dimensions_citation
4 Dimensions

Readers on

mendeley
17 Mendeley
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1 CiteULike
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Title
Assessing the joint effect of population stratification and sample selection in studies of gene-gene (environment) interactions
Published in
BMC Genomic Data, January 2012
DOI 10.1186/1471-2156-13-5
Pubmed ID
Authors

KF Cheng, JY Lee

Abstract

It is well known that the presence of population stratification (PS) may cause the usual test in case-control studies to produce spurious gene-disease associations. However, the impact of the PS and sample selection (SS) is less known. In this paper, we provide a systematic study of the joint effect of PS and SS under a more general risk model containing genetic and environmental factors. We provide simulation results to show the magnitude of the bias and its impact on type I error rate of the usual chi-square test under a wide range of PS level and selection bias.

X Demographics

X Demographics

The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 17 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 17 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 5 29%
Student > Ph. D. Student 4 24%
Student > Master 3 18%
Professor 2 12%
Professor > Associate Professor 1 6%
Other 1 6%
Unknown 1 6%
Readers by discipline Count As %
Medicine and Dentistry 4 24%
Agricultural and Biological Sciences 3 18%
Mathematics 2 12%
Computer Science 2 12%
Nursing and Health Professions 1 6%
Other 3 18%
Unknown 2 12%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 February 2012.
All research outputs
#3,710,178
of 25,374,647 outputs
Outputs from BMC Genomic Data
#116
of 1,204 outputs
Outputs of similar age
#28,993
of 252,391 outputs
Outputs of similar age from BMC Genomic Data
#1
of 16 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. Compared to these this one has done well and is in the 85th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,204 research outputs from this source. They receive a mean Attention Score of 4.3. This one has done particularly well, scoring higher than 90% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 252,391 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 16 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 93% of its contemporaries.