Title |
Noncoding RNA localisation mechanisms in chromatin regulation
|
---|---|
Published in |
Silence, January 2012
|
DOI | 10.1186/1758-907x-3-2 |
Pubmed ID | |
Authors |
Aditi Kanhere, Richard G Jenner |
Abstract |
An important challenge in biology has been to understand how cell-type-specific expression programs are orchestrated through regulated access to chromatin. Knowledge of the interaction between noncoding RNAs (ncRNAs) and chromatin regulators has the potential to help answer such questions, but how ncRNAs target chromatin regulators to specific sites in the genome is not well understood. Recently, Jeon and Lee proposed that DNA-binding proteins act as a bridge between ncRNAs and their target sites in chromatin. In this minireview, we examine their findings and place them in the wider context of how chromatin regulator-RNA complexes are targeted to specific sites in chromatin. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 3 | 60% |
Australia | 1 | 20% |
United Kingdom | 1 | 20% |
Demographic breakdown
Type | Count | As % |
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Scientists | 3 | 60% |
Members of the public | 2 | 40% |
Mendeley readers
Geographical breakdown
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United Kingdom | 4 | 4% |
Portugal | 1 | 1% |
Germany | 1 | 1% |
Italy | 1 | 1% |
Switzerland | 1 | 1% |
South Africa | 1 | 1% |
United States | 1 | 1% |
Unknown | 81 | 89% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 31 | 34% |
Student > Ph. D. Student | 21 | 23% |
Student > Master | 7 | 8% |
Student > Doctoral Student | 7 | 8% |
Student > Bachelor | 7 | 8% |
Other | 16 | 18% |
Unknown | 2 | 2% |
Readers by discipline | Count | As % |
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Biochemistry, Genetics and Molecular Biology | 23 | 25% |
Computer Science | 4 | 4% |
Medicine and Dentistry | 3 | 3% |
Unspecified | 1 | 1% |
Other | 4 | 4% |
Unknown | 1 | 1% |