@jasondeandc @NutriDetect It appears that Ivermectin can influence expression/function of p-glycoprotein thus allowing more into brain. BUT at what doses? Were there other drugs on board that also alter p-glycoprotein? Was p-g;ycoprotein already altered by
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RT @DrKatscom: @eBail_LLC @danawhite @thorne @joerogan @P_McCulloughMD "P-glycoprotein is an integral component of the human blood brain ba…
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@eBail_LLC @danawhite @thorne @joerogan @P_McCulloughMD "P-glycoprotein is an integral component of the human blood brain barrier & plays central role in limiting drug uptake into the brain. Altered expression / function allows elevation of brain conce
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@mama4mito @NaturallyFTW I'm not sure if its a clinically significant issue, but one thing I would note is that quercetin and curcumin appear to be p glycoprotein inhibitors. Pgp is needed to actively keep ivermectin out of the CNS, preventing GABA recept