@PaulTho50940982 Very interesting paper, which leads me to think that the current surfactants need improvement to have a chance of being effective The latest 2019 meta-analysis of RCTs re: surfactant in ARDS found no benefit https://t.co/wDiC9B9Afi
@beyukito Aunque se ha valorado incluso desde los 90s para el SDRA, hay varios problemas. En primer lugar, a diferencia de en el neonato, la disfunción del surfactante no es homogenea en el pulmón y un importante componente inflamatorio. https://t.co/HT7f
Interesting.
@IrinaYelinevich @PulmCrit Given alveolar damage and capillary permeability, it would be inactivated. I do not think it would work. It has been tried in ARDS before https://t.co/i3qPa2lJiw https://t.co/eJyLgf9IKl