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Involvement of the atrial natriuretic peptide in cardiovascular pathophysiology and its relationship with exercise

Overview of attention for article published in International Archives of Medicine, February 2012
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Title
Involvement of the atrial natriuretic peptide in cardiovascular pathophysiology and its relationship with exercise
Published in
International Archives of Medicine, February 2012
DOI 10.1186/1755-7682-5-4
Pubmed ID
Authors

Júlio C de Almeida, Clodoaldo L Alves, Luiz Carlos de Abreu, Monica A Sato, Fernando L Fonseca, Carlos B de Mello Monteiro, Luiz Carlos M Vanderlei, Hugo Macedo, Carlos M Tavares, Dafne Herrero, Luciano MR Rodrigues, Vitor E Valenti

Abstract

In this minireview we describe the involvement of the atrial natriuretic peptide (ANP) in cardiovascular pathophysiology and exercise. The ANP has a broad homeostatic role and exerts complex effects on the cardio-circulatory hemodynamics, it is produced by the left atrium and has a key role in regulating sodium and water balance in mammals and humans. The dominant stimulus for its release is atrial wall tension, commonly caused by exercise. The ANP is involved in the process of lipolysis through a cGMP signaling pathway and, as a consequence, reducing blood pressure by decreasing the sensitivity of vascular smooth muscle to the action of vasoconstrictors and regulate fluid balance. The increase of this hormone is associated with better survival in patients with chronic heart failure (CHF). This minireview provides new evidence based on recent studies related to the beneficial effects of exercise in patients with cardiovascular disease, focusing on the ANP.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 26 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 4%
Unknown 25 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 6 23%
Researcher 5 19%
Student > Bachelor 4 15%
Professor 2 8%
Student > Master 1 4%
Other 3 12%
Unknown 5 19%
Readers by discipline Count As %
Medicine and Dentistry 4 15%
Agricultural and Biological Sciences 4 15%
Biochemistry, Genetics and Molecular Biology 3 12%
Psychology 2 8%
Neuroscience 2 8%
Other 5 19%
Unknown 6 23%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 February 2012.
All research outputs
#20,656,161
of 25,374,647 outputs
Outputs from International Archives of Medicine
#81
of 103 outputs
Outputs of similar age
#205,286
of 253,982 outputs
Outputs of similar age from International Archives of Medicine
#5
of 6 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 103 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.1. This one is in the 9th percentile – i.e., 9% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 253,982 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 8th percentile – i.e., 8% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 6 others from the same source and published within six weeks on either side of this one.