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Target gene expression levels and competition between transfected and endogenous microRNAs are strong confounding factors in microRNA high-throughput experiments

Overview of attention for article published in Silence, February 2012
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Title
Target gene expression levels and competition between transfected and endogenous microRNAs are strong confounding factors in microRNA high-throughput experiments
Published in
Silence, February 2012
DOI 10.1186/1758-907x-3-3
Pubmed ID
Authors

Takaya Saito, Pål Sætrom

Abstract

MicroRNA (miRNA) target genes tend to have relatively long and conserved 3' untranslated regions (UTRs), but to what degree these characteristics contribute to miRNA targeting is poorly understood. Different high-throughput experiments have, for example, shown that miRNAs preferentially regulate genes with both short and long 3' UTRs and that target site conservation is both important and irrelevant for miRNA targeting.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 59 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 1 2%
France 1 2%
Denmark 1 2%
Korea, Republic of 1 2%
Thailand 1 2%
Unknown 54 92%

Demographic breakdown

Readers by professional status Count As %
Researcher 19 32%
Student > Ph. D. Student 13 22%
Student > Master 8 14%
Professor > Associate Professor 4 7%
Student > Doctoral Student 4 7%
Other 7 12%
Unknown 4 7%
Readers by discipline Count As %
Agricultural and Biological Sciences 36 61%
Biochemistry, Genetics and Molecular Biology 10 17%
Computer Science 3 5%
Pharmacology, Toxicology and Pharmaceutical Science 2 3%
Medicine and Dentistry 2 3%
Other 2 3%
Unknown 4 7%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 February 2012.
All research outputs
#16,580,596
of 25,374,917 outputs
Outputs from Silence
#24
of 28 outputs
Outputs of similar age
#168,548
of 255,036 outputs
Outputs of similar age from Silence
#3
of 3 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 34th percentile – i.e., 34% of other outputs scored the same or lower than it.
So far Altmetric has tracked 28 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.8. This one scored the same or higher as 4 of them.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 255,036 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 33rd percentile – i.e., 33% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 3 others from the same source and published within six weeks on either side of this one.