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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Emerging roles of Nrf2 signal in non-small cell lung cancer
|
|---|---|
| Published in |
Journal of Hematology & Oncology, February 2016
|
| DOI | 10.1186/s13045-016-0246-5 |
| Pubmed ID | |
| Authors |
Yijun Tian, Qian Liu, Xuelian He, Xun Yuan, Yuan Chen, Qian Chu, Kongming Wu |
| Abstract |
Non-small cell lung cancer (NSCLC) causes considerable mortality in the world. Owing to molecular biological progress, treatments in adenocarcinoma have evolved revolutionarily while those in squamous lung cancer remain unsatisfied. Recent studies revealed high-frequency alteration of Kelch-like ECH-associated protein 1/nuclear factor erythroid 2-like factor 2 (Keap1/Nrf2) pathway within squamous lung cancer, attracting researchers to focus on this particular pathway. In NSCLC patients, deregulated Nrf2 signal is recognized as a common feature at both DNA and protein level. Emerging associations between Nrf2 and other pathways have been elucidated. MicroRNA was also implicated in the regulation of Nrf2. Agents activating or antagonizing Nrf2 showed an effect in preclinical researches, reflecting different effects of Nrf2 during tumor initiation and progression. Prognostic evaluation demonstrated a negative impact of Nrf2 signal on NSCLC patients' survival. Considering the importance of Nrf2 signal in NSCLC, further studies are required in the future. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 2 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Science communicators (journalists, bloggers, editors) | 1 | 50% |
| Members of the public | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 56 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 2% |
| Unknown | 55 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 12 | 21% |
| Student > Ph. D. Student | 10 | 18% |
| Student > Bachelor | 8 | 14% |
| Other | 6 | 11% |
| Student > Doctoral Student | 4 | 7% |
| Other | 6 | 11% |
| Unknown | 10 | 18% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 13 | 23% |
| Medicine and Dentistry | 10 | 18% |
| Agricultural and Biological Sciences | 9 | 16% |
| Pharmacology, Toxicology and Pharmaceutical Science | 5 | 9% |
| Nursing and Health Professions | 2 | 4% |
| Other | 4 | 7% |
| Unknown | 13 | 23% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 March 2017.
All research outputs
#14,252,067
of 22,852,911 outputs
Outputs from Journal of Hematology & Oncology
#680
of 1,192 outputs
Outputs of similar age
#156,372
of 297,542 outputs
Outputs of similar age from Journal of Hematology & Oncology
#8
of 29 outputs
Altmetric has tracked 22,852,911 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,192 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.7. This one is in the 39th percentile – i.e., 39% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 297,542 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 44th percentile – i.e., 44% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 29 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 65% of its contemporaries.