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Mendeley readers
Attention Score in Context
Title |
Systemic treatment with liver X receptor agonists raises apolipoprotein E, cholesterol, and amyloid-β peptides in the cerebral spinal fluid of rats
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Published in |
Molecular Neurodegeneration, October 2010
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DOI | 10.1186/1750-1326-5-44 |
Pubmed ID | |
Authors |
Sokreine Suon, Jie Zhao, Stephanie A Villarreal, Nikesh Anumula, Mali Liu, Linda M Carangia, John J Renger, Celina V Zerbinatti |
Abstract |
Apolipoprotein E (apoE) is a major cholesterol transport protein found in association with brain amyloid from Alzheimer's disease (AD) patients and the ε4 allele of apoE is a genetic risk factor for AD. Previous studies have shown that apoE forms a stable complex with amyloid β (Aβ) peptides in vitro and that the state of apoE lipidation influences the fate of brain Aβ, i.e., lipid poor apoE promotes Aβ aggregation/deposition while fully lipidated apoE favors Aβ degradation/clearance. In the brain, apoE levels and apoE lipidation are regulated by the liver X receptors (LXRs). |
Mendeley readers
The data shown below were compiled from readership statistics for 34 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 6% |
Netherlands | 1 | 3% |
Unknown | 31 | 91% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 9 | 26% |
Student > Ph. D. Student | 6 | 18% |
Student > Master | 6 | 18% |
Professor > Associate Professor | 4 | 12% |
Student > Bachelor | 3 | 9% |
Other | 3 | 9% |
Unknown | 3 | 9% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 11 | 32% |
Neuroscience | 8 | 24% |
Biochemistry, Genetics and Molecular Biology | 5 | 15% |
Chemistry | 2 | 6% |
Sports and Recreations | 1 | 3% |
Other | 2 | 6% |
Unknown | 5 | 15% |
Attention Score in Context
This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 March 2021.
All research outputs
#2,722,030
of 22,662,201 outputs
Outputs from Molecular Neurodegeneration
#359
of 842 outputs
Outputs of similar age
#11,473
of 99,345 outputs
Outputs of similar age from Molecular Neurodegeneration
#1
of 6 outputs
Altmetric has tracked 22,662,201 research outputs across all sources so far. Compared to these this one has done well and is in the 87th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 842 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 14.0. This one has gotten more attention than average, scoring higher than 57% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 99,345 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 6 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them