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Comorbid epilepsy in Finnish patients with adult-onset Huntington’s disease

Overview of attention for article published in BMC Neurology, February 2016
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Title
Comorbid epilepsy in Finnish patients with adult-onset Huntington’s disease
Published in
BMC Neurology, February 2016
DOI 10.1186/s12883-016-0545-z
Pubmed ID
Authors

Jussi O. T. Sipilä, Merja Soilu-Hänninen, Kari Majamaa

Abstract

Seizures are common in juvenile Huntington's disease (HD), but considered to be rare in adult-onset HD. We studied the occurrence of epilepsy and seizures in a nationwide cohort of Finnish patients with adult-onset HD. Patients with HD and their diagnoses of epilepsy or seizures were identified by a search into a nationwide registry. Cases were verified in a subsequent review of patient charts. Three out of 114 HD patients alive on prevalence date had been diagnosed with epilepsy giving a prevalence of 2.6 % (95 % CI, 0.6-7.5). In addition, one patient with a single unprovoked seizure, one patient with a medication-induced seizure and two patients with transient nonspecific attacks were identified. Epilepsy was not associated with clinical severity of HD and seizures were controlled with antiepileptic medications (AEDs). Generalized tonic-clonic seizures (GTCs) were the most common seizure type. Prevalence of epilepsy is similar in patients with adult-onset HD compared to general population. Seizures are easily controlled with AEDs.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 36 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 36 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 8 22%
Student > Bachelor 6 17%
Student > Postgraduate 5 14%
Student > Master 5 14%
Student > Doctoral Student 4 11%
Other 7 19%
Unknown 1 3%
Readers by discipline Count As %
Medicine and Dentistry 17 47%
Pharmacology, Toxicology and Pharmaceutical Science 3 8%
Neuroscience 3 8%
Psychology 3 8%
Agricultural and Biological Sciences 2 6%
Other 5 14%
Unknown 3 8%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 February 2016.
All research outputs
#20,311,744
of 22,852,911 outputs
Outputs from BMC Neurology
#2,142
of 2,437 outputs
Outputs of similar age
#337,028
of 400,536 outputs
Outputs of similar age from BMC Neurology
#33
of 35 outputs
Altmetric has tracked 22,852,911 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,437 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.7. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 400,536 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 35 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.