Title |
ICGE: an R package for detecting relevant clusters and atypical units in gene expression
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Published in |
BMC Bioinformatics, February 2012
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DOI | 10.1186/1471-2105-13-30 |
Pubmed ID | |
Authors |
Itziar Irigoien, Basilio Sierra, Concepcion Arenas |
Abstract |
Gene expression technologies have opened up new ways to diagnose and treat cancer and other diseases. Clustering algorithms are a useful approach with which to analyze genome expression data. They attempt to partition the genes into groups exhibiting similar patterns of variation in expression level. An important problem associated with gene classification is to discern whether the clustering process can find a relevant partition as well as the identification of new genes classes. There are two key aspects to classification: the estimation of the number of clusters, and the decision as to whether a new unit (gene, tumor sample...) belongs to one of these previously identified clusters or to a new group. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Spain | 1 | 3% |
Colombia | 1 | 3% |
United States | 1 | 3% |
Norway | 1 | 3% |
Unknown | 33 | 89% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 12 | 32% |
Student > Ph. D. Student | 9 | 24% |
Professor | 4 | 11% |
Student > Doctoral Student | 2 | 5% |
Student > Bachelor | 2 | 5% |
Other | 6 | 16% |
Unknown | 2 | 5% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 17 | 46% |
Computer Science | 5 | 14% |
Biochemistry, Genetics and Molecular Biology | 4 | 11% |
Medicine and Dentistry | 3 | 8% |
Mathematics | 2 | 5% |
Other | 3 | 8% |
Unknown | 3 | 8% |