Title |
A patient with hypereosinophilic syndrome that manifested with acquired hemophilia and elevated IgG4: a case report
|
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Published in |
Journal of Medical Case Reports, February 2012
|
DOI | 10.1186/1752-1947-6-63 |
Pubmed ID | |
Authors |
Yoshiro Nagao, Hiromi Yamanaka, Hiromasa Harada |
Abstract |
Hypereosinophilic syndrome is defined as a prolonged state (more than six months) of eosinophilia (greater than 1500 cells/μL), without an apparent etiology and with end-organ damage. Hypereosinophilic syndrome can cause coagulation abnormalities. Among hypereosinophilic syndrome types, the lymphocytic variant (lymphocytic hypereosinophilic syndrome) is derived from a monoclonal proliferation of T lymphocytes. Here, we describe the case of a patient with lymphocytic hypereosinophilic syndrome who presented with a coagulation abnormality. To the best of our knowledge, this is the first such report including a detailed clinical picture and temporal cytokine profile. |
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