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Attention Score in Context
| Title |
Japanese encephalitis virus tropism in experimentally infected pigs
|
|---|---|
| Published in |
Veterinary Research, February 2016
|
| DOI | 10.1186/s13567-016-0319-z |
| Pubmed ID | |
| Authors |
Meret E. Ricklin, Obdulio Garcìa-Nicolàs, Daniel Brechbühl, Sylvie Python, Beatrice Zumkehr, Horst Posthaus, Anna Oevermann, Artur Summerfield |
| Abstract |
Pigs are considered to be the main amplifying host for Japanese encephalitis virus (JEV), and their infection can correlate with human cases of disease. Despite their importance in the ecology of the virus as it relates to human cases of encephalitis, the pathogenesis of JEV in pigs remains obscure. In the present study, the localization and kinetics of virus replication were investigated in various tissues after experimental intravenous infection of pigs. The data demonstrate a rapid and broad spreading of the virus to the central nervous system (CNS) and various other organs. A particular tropism of JEV in pigs not only to the CNS but also for secondary lymphoid tissue, in particular the tonsils with the overall highest viral loads, was observed. In this organ, even 11 days post infection, the latest time point of the experiment, no apparent decrease in viral RNA loads and live virus was found despite the presence of a neutralizing antibody response. This was also well beyond the clinical and viremic phase. These results are of significance for the pathogenesis of JEV, and call for further experimental studies focusing on the cellular source and duration of virus replication in pigs. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | 50% |
| Spain | 1 | 25% |
| Unknown | 1 | 25% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 4 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 88 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 88 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 13 | 15% |
| Student > Master | 11 | 13% |
| Other | 9 | 10% |
| Student > Ph. D. Student | 7 | 8% |
| Student > Bachelor | 6 | 7% |
| Other | 17 | 19% |
| Unknown | 25 | 28% |
| Readers by discipline | Count | As % |
|---|---|---|
| Veterinary Science and Veterinary Medicine | 14 | 16% |
| Agricultural and Biological Sciences | 12 | 14% |
| Biochemistry, Genetics and Molecular Biology | 11 | 13% |
| Medicine and Dentistry | 8 | 9% |
| Nursing and Health Professions | 2 | 2% |
| Other | 15 | 17% |
| Unknown | 26 | 30% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 September 2016.
All research outputs
#14,784,344
of 25,374,647 outputs
Outputs from Veterinary Research
#627
of 1,337 outputs
Outputs of similar age
#149,263
of 313,159 outputs
Outputs of similar age from Veterinary Research
#9
of 25 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one is in the 41st percentile – i.e., 41% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,337 research outputs from this source. They receive a mean Attention Score of 5.0. This one has gotten more attention than average, scoring higher than 52% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 313,159 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 51% of its contemporaries.
We're also able to compare this research output to 25 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 64% of its contemporaries.