Title |
Global host metabolic response to Plasmodium vivax infection: a 1H NMR based urinary metabonomic study
|
---|---|
Published in |
Malaria Journal, December 2011
|
DOI | 10.1186/1475-2875-10-384 |
Pubmed ID | |
Authors |
Arjun Sengupta, Soumita Ghosh, Angika Basant, Suhas Malusare, Parul Johri, Sulabha Pathak, Shobhona Sharma, Haripalsingh M Sonawat |
Abstract |
Plasmodium vivax is responsible for the majority of malarial infection in the Indian subcontinent. This species of the parasite is generally believed to cause a relatively benign form of the disease. However, recent reports from different parts of the world indicate that vivax malaria can also have severe manifestation. Host response to the parasite invasion is thought to be an important factor in determining the severity of manifestation. In this paper, attempt was made to determine the host metabolic response associated with P. vivax infection by means of NMR spectroscopy-based metabonomic techniques in an attempt to better understand the disease pathology. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
India | 1 | 1% |
Unknown | 73 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 22 | 30% |
Student > Master | 10 | 14% |
Researcher | 9 | 12% |
Student > Bachelor | 4 | 5% |
Other | 3 | 4% |
Other | 9 | 12% |
Unknown | 17 | 23% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 17 | 23% |
Biochemistry, Genetics and Molecular Biology | 8 | 11% |
Medicine and Dentistry | 8 | 11% |
Chemistry | 7 | 9% |
Immunology and Microbiology | 3 | 4% |
Other | 10 | 14% |
Unknown | 21 | 28% |