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Relationships between serum HER2 ECD, TIMP-1 and clinical outcomes in Taiwanese breast cancer

Overview of attention for article published in World Journal of Surgical Oncology, February 2012
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Title
Relationships between serum HER2 ECD, TIMP-1 and clinical outcomes in Taiwanese breast cancer
Published in
World Journal of Surgical Oncology, February 2012
DOI 10.1186/1477-7819-10-42
Pubmed ID
Authors

Hsiu-Pei Tsai, Shin-Cheh Chen, Huei-Tzu Chien, Yi-Yin Jan, Tzu-Chieh Chao, Miin-Fu Chen, Ling-Ling Hsieh

Abstract

Serum levels of the extracellular domain of HER2/neu (HER2 ECD) have been demonstrated to be associated with clinical outcomes. A disintegrin and metalloproteinase-10, a sheddase of HER2/neu, can drive cancer progression and its activity is inhibited by tissue inhibitor of metalloproteinase-1 (TIMP-1). However, elevated TIMP-1 expression has been associated with a poor prognosis of breast cancer. Therefore, this study was performed to explore the relationships between serum HER2 ECD, TIMP-1 and clinical outcomes.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 21 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 21 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 9 43%
Other 2 10%
Researcher 2 10%
Student > Doctoral Student 1 5%
Student > Bachelor 1 5%
Other 3 14%
Unknown 3 14%
Readers by discipline Count As %
Medicine and Dentistry 10 48%
Agricultural and Biological Sciences 5 24%
Biochemistry, Genetics and Molecular Biology 2 10%
Neuroscience 1 5%
Chemistry 1 5%
Other 0 0%
Unknown 2 10%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 February 2012.
All research outputs
#18,304,874
of 22,663,150 outputs
Outputs from World Journal of Surgical Oncology
#1,025
of 2,038 outputs
Outputs of similar age
#121,660
of 156,209 outputs
Outputs of similar age from World Journal of Surgical Oncology
#22
of 51 outputs
Altmetric has tracked 22,663,150 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,038 research outputs from this source. They receive a mean Attention Score of 2.0. This one is in the 21st percentile – i.e., 21% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 156,209 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 9th percentile – i.e., 9% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 51 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.