The inherited variations of a p53-responsive enhancer in 13q12.12 confer lung cancer risk by attenuating TNFRSF19 expression https://t.co/Flj1AaREgi
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RT @tangming2005: The inherited variations of a p53-responsive enhancer in 13q12.12 confer lung cancer risk by attenuating TNFRSF19 express…
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The inherited variations of a p53-responsive enhancer in 13q12.12 confer lung cancer risk by attenuating TNFRSF19 expression https://t.co/xZseFWryKV
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Shao, Zuo, Yang, Song, Shen, Sun and co show that a SNP associated with lung cancer in GWAS of Chinese populations is in an enhancer. Variants reduce p53 binding, making cells more susceptible to DNA damage from NNK https://t.co/hc82kqj4Qc https://t.co/qaE