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Mendeley readers
Attention Score in Context
| Title |
Emerging Role of High-Mobility Group Box 1 (HMGB1) in Liver Diseases
|
|---|---|
| Published in |
Molecular Medicine, November 2013
|
| DOI | 10.2119/molmed.2013.00099 |
| Pubmed ID | |
| Authors |
Ruochan Chen, Wen Hou, Qiuhong Zhang, Rui Kang, Xue-Gong Fan, Daolin Tang |
| Abstract |
Damage-associated molecular pattern (DAMP) molecules are essential for the initiation of innate inflammatory responses to infection and injury. The prototypic DAMP molecule, high-mobility group box 1 (HMGB1), is an abundant architectural chromosomal protein that has location-specific biological functions: within the nucleus as a DNA chaperone, within the cytosol to sustain autophagy and outside the cell as a DAMP molecule. Recent research indicates that aberrant activation of HMGB1 signaling can promote the onset of inflammatory and autoimmune diseases, raising interest in the development of therapeutic strategies to control their function. The importance of HMGB1 activation in various forms of liver disease in relation to liver damage, steatosis, inflammation, fibrosis, tumorigenesis and regeneration is discussed in this review. |
Mendeley readers
The data shown below were compiled from readership statistics for 75 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Japan | 1 | 1% |
| Belgium | 1 | 1% |
| Unknown | 73 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 13 | 17% |
| Student > Ph. D. Student | 12 | 16% |
| Researcher | 9 | 12% |
| Student > Postgraduate | 6 | 8% |
| Student > Bachelor | 6 | 8% |
| Other | 15 | 20% |
| Unknown | 14 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 20 | 27% |
| Biochemistry, Genetics and Molecular Biology | 17 | 23% |
| Agricultural and Biological Sciences | 8 | 11% |
| Immunology and Microbiology | 5 | 7% |
| Pharmacology, Toxicology and Pharmaceutical Science | 2 | 3% |
| Other | 6 | 8% |
| Unknown | 17 | 23% |
Attention Score in Context
This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 March 2023.
All research outputs
#3,406,315
of 23,504,791 outputs
Outputs from Molecular Medicine
#125
of 1,176 outputs
Outputs of similar age
#32,601
of 217,294 outputs
Outputs of similar age from Molecular Medicine
#2
of 8 outputs
Altmetric has tracked 23,504,791 research outputs across all sources so far. Compared to these this one has done well and is in the 84th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,176 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one has done well, scoring higher than 86% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 217,294 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 84% of its contemporaries.
We're also able to compare this research output to 8 others from the same source and published within six weeks on either side of this one. This one has scored higher than 6 of them.