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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Oxford Lithium Trial (OxLith) of the early affective, cognitive, neural and biochemical effects of lithium carbonate in bipolar disorder: study protocol for a randomised controlled trial
|
|---|---|
| Published in |
Trials, March 2016
|
| DOI | 10.1186/s13063-016-1230-7 |
| Pubmed ID | |
| Authors |
Kate E. A. Saunders, Andrea Cipriani, Jennifer Rendell, Mary-Jane Attenburrow, Natalie Nelissen, Amy C. Bilderbeck, Sridhar R. Vasudevan, Grant Churchill, Guy M. Goodwin, Anna C. Nobre, Catherine J. Harmer, Paul J. Harrison, John R. Geddes |
| Abstract |
Despite lithium's being the most effective drug for bipolar disorder and in clinical use for decades, we still know very little about its early effects relevant to its mode of action. The Oxford Lithium Trial is a double-blind, randomised, placebo-controlled study of 6-week lithium treatment in participants with bipolar disorder and mood instability. Its aim is to identify early clinical, neurocognitive and biological effects. Participants (n = 40) will undergo an intensive battery of multi-modal investigations, including remote monitoring of mood, activity and physiology, as well as cognitive testing, fMRI and magnetoencephalography, together with biochemical and gene expression measurements to assess renal, inflammatory and circadian effects. The findings derived from this trial may be of value in predicting subsequent therapeutic response or side effects, not only relevant to the use of lithium but also providing a potential signature to help in more rapid evaluation of novel mood stabilisers. In this respect, OxLith is a step towards the development of a valid experimental medicine model for bipolar disorder. ISRCTN91624955 . Registered on 22 January 2015. |
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 135 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | 1% |
| Unknown | 133 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 20 | 15% |
| Student > Bachelor | 20 | 15% |
| Student > Master | 19 | 14% |
| Student > Postgraduate | 9 | 7% |
| Student > Ph. D. Student | 7 | 5% |
| Other | 23 | 17% |
| Unknown | 37 | 27% |
| Readers by discipline | Count | As % |
|---|---|---|
| Psychology | 30 | 22% |
| Medicine and Dentistry | 27 | 20% |
| Nursing and Health Professions | 9 | 7% |
| Neuroscience | 7 | 5% |
| Biochemistry, Genetics and Molecular Biology | 5 | 4% |
| Other | 14 | 10% |
| Unknown | 43 | 32% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 March 2016.
All research outputs
#21,262,208
of 26,110,873 outputs
Outputs from Trials
#5,349
of 6,611 outputs
Outputs of similar age
#233,332
of 314,300 outputs
Outputs of similar age from Trials
#107
of 122 outputs
Altmetric has tracked 26,110,873 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 6,611 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one is in the 9th percentile – i.e., 9% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 314,300 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 13th percentile – i.e., 13% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 122 others from the same source and published within six weeks on either side of this one. This one is in the 7th percentile – i.e., 7% of its contemporaries scored the same or lower than it.