Title |
RNA interference targeting virion core protein ORF095 inhibits Goatpox virus replication in Vero cells
|
---|---|
Published in |
Virology Journal, February 2012
|
DOI | 10.1186/1743-422x-9-48 |
Pubmed ID | |
Authors |
Zhixun Zhao, Guohua Wu, Xueliang Zhu, Xinmin Yan, Yongxi Dou, Jian Li, Haixia Zhu, Qiang Zhang, Xuepeng Cai |
Abstract |
Goatpox is an economically important disease in goat and sheep-producing areas of the world. Many vaccine strategies developed to control the disease are not yet completely successful. Hairpin expression vectors have been used to induce gene silencing in a large number of studies on viruses. However, none of these studies has been attempted to study GTPV. In the interest of exploiting improved methods to control goat pox, it is participated that RNAi may provide effective protection against GTPV. In this study we show the suppression of Goatpox virus (GTPV) replication via knockdown of virion core protein using RNA interference. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 15 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 5 | 33% |
Researcher | 3 | 20% |
Student > Bachelor | 2 | 13% |
Student > Doctoral Student | 1 | 7% |
Professor > Associate Professor | 1 | 7% |
Other | 1 | 7% |
Unknown | 2 | 13% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 5 | 33% |
Veterinary Science and Veterinary Medicine | 3 | 20% |
Immunology and Microbiology | 1 | 7% |
Economics, Econometrics and Finance | 1 | 7% |
Medicine and Dentistry | 1 | 7% |
Other | 0 | 0% |
Unknown | 4 | 27% |