Title |
The impact of hyperbaric oxygen therapy on serological values of vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF)
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Published in |
Head & Face Medicine, December 2010
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DOI | 10.1186/1746-160x-6-29 |
Pubmed ID | |
Authors |
Susanne Jung, Kai Wermker, Harald Poetschik, Thomas Ziebura, Johannes Kleinheinz |
Abstract |
Hyperbaric oxygen (HBO) therapy is an effective adjunct treatment for ischemic disorders such as chronic infection or chronic wounds. It combines hyperoxic effects with the stimulating potential of post-therapeutic reactive hypoxia. As its crucial effects, stimulation of fibroblast growth, induction of collagen synthesis and the initiation of angiogenesis are discussed. Angiogenesis is a multistage process resulting in the growth of blood vessels. It includes degradation of extracellular matrix, proliferation and migration of different cell populations and finally formation of new vessel structures. This complex chain of procedures is orchestrated by different cytokines and growth factors. Crucial mediators of angiogenesis are basic fibroblast growth factor (bFGF) and vascular endothelial growth factor (VEGF); their in-vivo function is still not fully understood. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Mexico | 1 | 1% |
Spain | 1 | 1% |
Italy | 1 | 1% |
Australia | 1 | 1% |
Unknown | 65 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 12 | 17% |
Student > Ph. D. Student | 8 | 12% |
Student > Master | 8 | 12% |
Student > Bachelor | 6 | 9% |
Other | 5 | 7% |
Other | 14 | 20% |
Unknown | 16 | 23% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 35 | 51% |
Agricultural and Biological Sciences | 8 | 12% |
Nursing and Health Professions | 3 | 4% |
Business, Management and Accounting | 1 | 1% |
Arts and Humanities | 1 | 1% |
Other | 4 | 6% |
Unknown | 17 | 25% |