↓ Skip to main content

Renal expression and serum levels of high mobility group box 1 protein in lupus nephritis

Overview of attention for article published in Arthritis Research & Therapy, February 2012
Altmetric Badge

Citations

dimensions_citation
66 Dimensions

Readers on

mendeley
37 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Renal expression and serum levels of high mobility group box 1 protein in lupus nephritis
Published in
Arthritis Research & Therapy, February 2012
DOI 10.1186/ar3747
Pubmed ID
Authors

Agneta Zickert, Karin Palmblad, Birgitta Sundelin, Sangeeta Chavan, Kevin J Tracey, Annette Bruchfeld, Iva Gunnarsson

Abstract

High mobility group box 1 protein (HMGB1) is a nuclear DNA binding protein acting as a pro-inflammatory mediator following extracellular release. HMGB1 has been increasingly recognized as a pathogenic mediator in several inflammatory diseases. Elevated serum levels of HMGB1 have been detected in autoimmune diseases including Systemic lupus erythematosus (SLE). However, the local expression of HMGB1 in active lupus nephritis (LN) is not known. Here we aimed to study both tissue expression and serum levels of HMGB1 in LN patients with active disease and after induction therapy.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 37 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 3%
Unknown 36 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 10 27%
Student > Ph. D. Student 7 19%
Student > Postgraduate 4 11%
Professor 3 8%
Student > Bachelor 2 5%
Other 8 22%
Unknown 3 8%
Readers by discipline Count As %
Medicine and Dentistry 21 57%
Biochemistry, Genetics and Molecular Biology 3 8%
Agricultural and Biological Sciences 3 8%
Psychology 2 5%
Economics, Econometrics and Finance 1 3%
Other 2 5%
Unknown 5 14%