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GABA and glycine in the developing brain

Overview of attention for article published in The Journal of Physiological Sciences, March 2016
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  • Good Attention Score compared to outputs of the same age (67th percentile)
  • Average Attention Score compared to outputs of the same age and source

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5 X users
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1 Facebook page
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1 YouTube creator

Citations

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48 Dimensions

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79 Mendeley
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Title
GABA and glycine in the developing brain
Published in
The Journal of Physiological Sciences, March 2016
DOI 10.1007/s12576-016-0442-7
Pubmed ID
Authors

Susumu Ito

Abstract

GABA and glycine are major inhibitory neurotransmitters in the CNS and act on receptors coupled to chloride channels. During early developmental periods, both GABA and glycine depolarize membrane potentials due to the relatively high intracellular Cl(-) concentration. Therefore, they can act as excitatory neurotransmitters. GABA and glycine are involved in spontaneous neural network activities in the immature CNS such as giant depolarizing potentials (GDPs) in neonatal hippocampal neurons, which are generated by the synchronous activity of GABAergic interneurons and glutamatergic principal neurons. GDPs and GDP-like activities in the developing brains are thought to be important for the activity-dependent functiogenesis through Ca(2+) influx and/or other intracellular signaling pathways activated by depolarization or stimulation of metabotropic receptors. However, if GABA and glycine do not shift from excitatory to inhibitory neurotransmitters at the birth and in maturation, it may result in neural disorders including autism spectrum disorders.

X Demographics

X Demographics

The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 79 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 1 1%
Unknown 78 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 14 18%
Student > Master 13 16%
Student > Bachelor 12 15%
Student > Doctoral Student 6 8%
Researcher 5 6%
Other 10 13%
Unknown 19 24%
Readers by discipline Count As %
Neuroscience 23 29%
Biochemistry, Genetics and Molecular Biology 10 13%
Agricultural and Biological Sciences 8 10%
Nursing and Health Professions 4 5%
Medicine and Dentistry 4 5%
Other 8 10%
Unknown 22 28%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 September 2023.
All research outputs
#7,817,235
of 25,654,806 outputs
Outputs from The Journal of Physiological Sciences
#108
of 492 outputs
Outputs of similar age
#100,380
of 313,973 outputs
Outputs of similar age from The Journal of Physiological Sciences
#7
of 13 outputs
Altmetric has tracked 25,654,806 research outputs across all sources so far. This one has received more attention than most of these and is in the 69th percentile.
So far Altmetric has tracked 492 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.6. This one has done well, scoring higher than 77% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 313,973 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 67% of its contemporaries.
We're also able to compare this research output to 13 others from the same source and published within six weeks on either side of this one. This one is in the 46th percentile – i.e., 46% of its contemporaries scored the same or lower than it.