Title |
Misdiagnosis of primary hepatic marginal zone B cell lymphoma of mucosa-associated lymphoid tissue type, a case report
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Published in |
World Journal of Surgical Oncology, March 2016
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DOI | 10.1186/s12957-016-0817-5 |
Pubmed ID | |
Authors |
L. X. Li, S. T. Zhou, X. Ji, H. Ren, Y. L. Sun, J. B. Zhang, H. B. Wang, Z. W. Liu |
Abstract |
Extra-nodal marginal zone B cell lymphoma of mucosa-associated lymphoid tissue originating in the liver is less common. We described the clinical presentation, immunohistochemistry, and immunophenotypes of this lymphoma, which was misdiagnosed with tiny hepatic carcinoma in a 44-year-old woman with hepatitis C; the patient underwent left lateral sectionectomy. The immunophenotype identified the most of the lymphoid cells as positive CD20, CD34, Ki67, CD3, CD4, CD79a, CD45RO, MUM-1, and CD5 and negative CD10, CD15, CD30, ACT, CK, CRO, DES, and HMB45. The diagnosis of primary hepatic mucosa-associated lymphoid tissue (MALT) was made by histology after surgery; the patient went through the excellent recovery with no chemotherapy and is disease free for 27 months. Primary hepatic MALT is less common with incidental finding; local resection is beneficial due to its oncological indolence. |
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