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A SCN9A gene-encoded dorsal root ganglia sodium channel polymorphism associated with severe fibromyalgia

Overview of attention for article published in BMC Musculoskeletal Disorders, February 2012
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (82nd percentile)
  • High Attention Score compared to outputs of the same age and source (86th percentile)

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4 X users
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5 Facebook pages
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5 Wikipedia pages

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97 Mendeley
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Title
A SCN9A gene-encoded dorsal root ganglia sodium channel polymorphism associated with severe fibromyalgia
Published in
BMC Musculoskeletal Disorders, February 2012
DOI 10.1186/1471-2474-13-23
Pubmed ID
Authors

Gilberto Vargas-Alarcon, Edith Alvarez-Leon, Jose-Manuel Fragoso, Angelica Vargas, Aline Martinez, Maite Vallejo, Manuel Martinez-Lavin

Abstract

A consistent line of investigation suggests that autonomic nervous system dysfunction may explain the multi-system features of fibromyalgia (FM); and that FM is a sympathetically maintained neuropathic pain syndrome. Dorsal root ganglia (DRG) are key sympathetic-nociceptive short-circuit sites. Sodium channels located in DRG (particularly Nav1.7) act as molecular gatekeepers for pain detection. Nav1.7 is encoded in gene SCN9A of chromosome 2q24.3 and is predominantly expressed in the DRG pain-sensing neurons and sympathetic ganglia neurons. Several SCN9A sodium channelopathies have been recognized as the cause of rare painful dysautonomic syndromes such as paroxysmal extreme pain disorder and primary erythromelalgia. The aim of this study was to search for an association between fibromyalgia and several SCN9A sodium channels gene polymorphisms.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 97 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 1%
Germany 1 1%
Australia 1 1%
Unknown 94 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 20 21%
Student > Master 16 16%
Student > Bachelor 13 13%
Student > Ph. D. Student 12 12%
Student > Doctoral Student 6 6%
Other 17 18%
Unknown 13 13%
Readers by discipline Count As %
Medicine and Dentistry 30 31%
Agricultural and Biological Sciences 11 11%
Neuroscience 8 8%
Biochemistry, Genetics and Molecular Biology 5 5%
Psychology 5 5%
Other 18 19%
Unknown 20 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 January 2024.
All research outputs
#4,077,123
of 22,663,150 outputs
Outputs from BMC Musculoskeletal Disorders
#806
of 4,022 outputs
Outputs of similar age
#26,490
of 156,574 outputs
Outputs of similar age from BMC Musculoskeletal Disorders
#5
of 37 outputs
Altmetric has tracked 22,663,150 research outputs across all sources so far. Compared to these this one has done well and is in the 81st percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,022 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.0. This one has done well, scoring higher than 79% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 156,574 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 82% of its contemporaries.
We're also able to compare this research output to 37 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 86% of its contemporaries.