↓ Skip to main content

Association of IREB2 and CHRNA3polymorphisms with airflow obstruction in severe alpha-1 antitrypsin deficiency

Overview of attention for article published in Respiratory Research, February 2012
Altmetric Badge

Mentioned by

twitter
2 X users

Citations

dimensions_citation
46 Dimensions

Readers on

mendeley
45 Mendeley
citeulike
1 CiteULike
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Association of IREB2 and CHRNA3polymorphisms with airflow obstruction in severe alpha-1 antitrypsin deficiency
Published in
Respiratory Research, February 2012
DOI 10.1186/1465-9921-13-16
Pubmed ID
Authors

Woo Jin Kim, Alice M Wood, Alan F Barker, Mark L Brantly, Edward J Campbell, Edward Eden, Gerard McElvaney, Stephen I Rennard, Robert A Sandhaus, James M Stocks, James K Stoller, Charlie Strange, Gerard Turino, Edwin K Silverman, Robert A Stockley, Dawn L DeMeo

Abstract

The development of COPD in subjects with alpha-1 antitrypsin (AAT) deficiency is likely to be influenced by modifier genes. Genome-wide association studies and integrative genomics approaches in COPD have demonstrated significant associations with SNPs in the chromosome 15q region that includes CHRNA3 (cholinergic nicotine receptor alpha3) and IREB2 (iron regulatory binding protein 2).We investigated whether SNPs in the chromosome 15q region would be modifiers for lung function and COPD in AAT deficiency.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 45 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 2%
Canada 1 2%
Unknown 43 96%

Demographic breakdown

Readers by professional status Count As %
Researcher 9 20%
Student > Master 7 16%
Student > Bachelor 4 9%
Student > Ph. D. Student 4 9%
Other 4 9%
Other 5 11%
Unknown 12 27%
Readers by discipline Count As %
Medicine and Dentistry 18 40%
Agricultural and Biological Sciences 6 13%
Biochemistry, Genetics and Molecular Biology 4 9%
Economics, Econometrics and Finance 2 4%
Computer Science 1 2%
Other 3 7%
Unknown 11 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 February 2012.
All research outputs
#19,944,091
of 25,373,627 outputs
Outputs from Respiratory Research
#2,510
of 3,062 outputs
Outputs of similar age
#129,113
of 169,132 outputs
Outputs of similar age from Respiratory Research
#18
of 19 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 18th percentile – i.e., 18% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,062 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.9. This one is in the 11th percentile – i.e., 11% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 169,132 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 21st percentile – i.e., 21% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 19 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.