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Multifaceted functions and roles of HBZ in HTLV-1 pathogenesis

Overview of attention for article published in Retrovirology, March 2016
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (53rd percentile)
  • Good Attention Score compared to outputs of the same age and source (65th percentile)

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5 X users
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1 Facebook page

Citations

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103 Dimensions

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82 Mendeley
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Title
Multifaceted functions and roles of HBZ in HTLV-1 pathogenesis
Published in
Retrovirology, March 2016
DOI 10.1186/s12977-016-0249-x
Pubmed ID
Authors

Guangyong Ma, Jun-ichirou Yasunaga, Masao Matsuoka

Abstract

Human T cell leukemia virus type 1 (HTLV-1) is an oncogenic retrovirus responsible for the development of adult T-cell leukemia (ATL). Although HTLV-1 harbors an oncogene, tax, that transforms T cells in vitro and induces leukemia in transgenic mice, tax expression is frequently disrupted in ATL, making the oncogenesis of ATL a bit mysterious. The HTLV-1 bZIP factor (HBZ) gene was discovered in 2002 and has been found to promote T-cell proliferation and cause lymphoma in transgenic mice. Thus HBZ has become a novel hotspot of HTLV-1 research. This review summarizes the current findings on HBZ with a special focus on its potential links to the oncogenesis of ATL. We propose viewing HBZ as a critical contributing factor in ATL development.

X Demographics

X Demographics

The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 82 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Israel 1 1%
Brazil 1 1%
Unknown 80 98%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 21 26%
Student > Ph. D. Student 11 13%
Researcher 11 13%
Student > Master 10 12%
Student > Postgraduate 5 6%
Other 12 15%
Unknown 12 15%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 23 28%
Medicine and Dentistry 13 16%
Agricultural and Biological Sciences 13 16%
Immunology and Microbiology 11 13%
Nursing and Health Professions 4 5%
Other 6 7%
Unknown 12 15%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 March 2016.
All research outputs
#12,950,089
of 22,856,968 outputs
Outputs from Retrovirology
#574
of 1,107 outputs
Outputs of similar age
#136,302
of 299,392 outputs
Outputs of similar age from Retrovirology
#7
of 23 outputs
Altmetric has tracked 22,856,968 research outputs across all sources so far. This one is in the 42nd percentile – i.e., 42% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,107 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.1. This one is in the 46th percentile – i.e., 46% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 299,392 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 53% of its contemporaries.
We're also able to compare this research output to 23 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 65% of its contemporaries.