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Molecular characterization of human Cryptosporidium spp. isolates after an unusual increase in late summer 2012

Overview of attention for article published in Parasites & Vectors, March 2016
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Title
Molecular characterization of human Cryptosporidium spp. isolates after an unusual increase in late summer 2012
Published in
Parasites & Vectors, March 2016
DOI 10.1186/s13071-016-1397-5
Pubmed ID
Authors

Jeroen H. Roelfsema, Hein Sprong, Simone M. Cacciò, Katsuhisa Takumi, Michiel Kroes, Wilfrid van Pelt, Laetitia M. Kortbeek, Joke W. B. van der Giessen

Abstract

During the late summer 2012, a number of medical microbiological laboratories (MMLs) reported an unusual increase in cases of cryptosporidiosis, a gastrointestinal infection caused by the protozoan parasites Cryptosporidium spp. Prompted by this signal, the National Institute of Public Health and the Environment (RIVM) started an epidemiological investigation into possible causes. Simultaneously, samples diagnosed at MMLs were sent to RIVM for genotyping, aiming to further identify the possible source of the increase. Genotyping was performed by sequencing a fragment of the GP60 gene. Additional genotyping was performed on a subset of samples using six microsatellite markers. Population genetic analysis was performed using BEAST. The majority of the samples were typed as C. hominis, and a single GP60 genotype (IbA10G2) largely predominated. Genotyping microsatellite markers further supported the circulation of a single genetic type. Population genetic analysis with genotypes found in previous years is inconsistent with a decrease in effective population size. The conclusion of this finding is that the rise reflects more an overall increase and not a common source outbreak.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 34 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 34 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 6 18%
Student > Ph. D. Student 5 15%
Student > Master 4 12%
Student > Bachelor 3 9%
Student > Doctoral Student 2 6%
Other 5 15%
Unknown 9 26%
Readers by discipline Count As %
Immunology and Microbiology 10 29%
Agricultural and Biological Sciences 5 15%
Biochemistry, Genetics and Molecular Biology 4 12%
Medicine and Dentistry 4 12%
Unspecified 1 3%
Other 1 3%
Unknown 9 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 March 2016.
All research outputs
#18,447,592
of 22,856,968 outputs
Outputs from Parasites & Vectors
#4,231
of 5,470 outputs
Outputs of similar age
#218,355
of 300,116 outputs
Outputs of similar age from Parasites & Vectors
#142
of 177 outputs
Altmetric has tracked 22,856,968 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 5,470 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one is in the 11th percentile – i.e., 11% of its peers scored the same or lower than it.
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We're also able to compare this research output to 177 others from the same source and published within six weeks on either side of this one. This one is in the 10th percentile – i.e., 10% of its contemporaries scored the same or lower than it.