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Acceptability of study procedures (self-collected introital swabs, blood draws and stool sample collection) by students 10–16 years for an HPV vaccine effectiveness study: a pilot study

Overview of attention for article published in BMC Research Notes, March 2016
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Title
Acceptability of study procedures (self-collected introital swabs, blood draws and stool sample collection) by students 10–16 years for an HPV vaccine effectiveness study: a pilot study
Published in
BMC Research Notes, March 2016
DOI 10.1186/s13104-016-1984-8
Pubmed ID
Authors

Miriam Nakalembe, Twaha Mutyaba, Florence Mirembe

Abstract

A cohort study was planned to evaluate vaccine immunogenicity and effect of malaria and helminth co-infections on the bivalent Human papilloma virus (HPV) vaccine. The study would involve self collected introital swabs, blood draws and stool sample collection. We therefore conducted a pilot study to assess the acceptability of these procedures among the students and their parents. A cross-sectional study among forty four students from two purposively selected primary schools of Western Uganda. Exit interviews and two focus group discussions (FGD) (for parents) were conducted. Acceptability was measured by willingness to undergo the procedures again, recommending the procedures to others as well as proportion of introital swabs positive for β globulin. FGD determined acceptability of the parents and explored opinions and perceptions that would influence their decisions. HPV-16/18 and β globulin deoxyribonucleic acid (DNA) were analysed using a polymerase chain reaction (PCR) kit. All the students (100 %) in the study were willing to provide a self- collected introital swab and a stool sample as well as recommending their friends while (86.3 %) were willing for blood draws. There were 40/44 (90.1 %) self collected introital swabs that had positive result for human β globulin though none of them was positive for HPV-16/18. In the FGD, it emerged that parents concerns were on the blood draws and introital swab collection which were addressed. The study procedures were highly acceptable among this study population of students and their parents. Follow-up to assess HPV vaccine effectiveness and factors that may influence the vaccine in this age group is feasible.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 51 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 1 2%
Unknown 50 98%

Demographic breakdown

Readers by professional status Count As %
Student > Master 18 35%
Researcher 8 16%
Student > Bachelor 7 14%
Student > Doctoral Student 2 4%
Professor > Associate Professor 2 4%
Other 6 12%
Unknown 8 16%
Readers by discipline Count As %
Medicine and Dentistry 16 31%
Nursing and Health Professions 8 16%
Social Sciences 6 12%
Pharmacology, Toxicology and Pharmaceutical Science 2 4%
Biochemistry, Genetics and Molecular Biology 1 2%
Other 8 16%
Unknown 10 20%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 March 2016.
All research outputs
#5,603,195
of 7,406,294 outputs
Outputs from BMC Research Notes
#1,293
of 1,878 outputs
Outputs of similar age
#208,567
of 297,162 outputs
Outputs of similar age from BMC Research Notes
#78
of 114 outputs
Altmetric has tracked 7,406,294 research outputs across all sources so far. This one is in the 13th percentile – i.e., 13% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,878 research outputs from this source. They receive a mean Attention Score of 4.6. This one is in the 16th percentile – i.e., 16% of its peers scored the same or lower than it.
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We're also able to compare this research output to 114 others from the same source and published within six weeks on either side of this one. This one is in the 14th percentile – i.e., 14% of its contemporaries scored the same or lower than it.