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Gene silencing of IL-12 in dendritic cells inhibits autoimmune arthritis

Overview of attention for article published in Journal of Translational Medicine, January 2012
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2 X users

Citations

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39 Dimensions

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33 Mendeley
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Title
Gene silencing of IL-12 in dendritic cells inhibits autoimmune arthritis
Published in
Journal of Translational Medicine, January 2012
DOI 10.1186/1479-5876-10-19
Pubmed ID
Authors

Rong Li, Xiufen Zheng, Igor Popov, Xusheng Zhang, Hongmei Wang, Motohiko Suzuki, Rosalia De Necochea-Campion, Peter W French, Di Chen, Leo Siu, David Koos, Robert D Inman, Wei-Ping Min

Abstract

We have previously demonstrated that immune modulation can be accomplished by administration of gene silenced dendritic cells (DC) using siRNA. In this study, we demonstrate the therapeutic utilization of shRNA-modified DC as an antigen-specific tolerogenic vaccine strategy for autoimmune arthritis.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 33 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 33 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 9 27%
Researcher 8 24%
Student > Master 7 21%
Student > Bachelor 3 9%
Professor 2 6%
Other 3 9%
Unknown 1 3%
Readers by discipline Count As %
Agricultural and Biological Sciences 9 27%
Medicine and Dentistry 8 24%
Immunology and Microbiology 5 15%
Pharmacology, Toxicology and Pharmaceutical Science 2 6%
Biochemistry, Genetics and Molecular Biology 2 6%
Other 3 9%
Unknown 4 12%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 February 2014.
All research outputs
#13,360,185
of 22,663,150 outputs
Outputs from Journal of Translational Medicine
#1,573
of 3,954 outputs
Outputs of similar age
#146,210
of 247,128 outputs
Outputs of similar age from Journal of Translational Medicine
#25
of 48 outputs
Altmetric has tracked 22,663,150 research outputs across all sources so far. This one is in the 39th percentile – i.e., 39% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,954 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.5. This one has gotten more attention than average, scoring higher than 57% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 247,128 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 39th percentile – i.e., 39% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 48 others from the same source and published within six weeks on either side of this one. This one is in the 45th percentile – i.e., 45% of its contemporaries scored the same or lower than it.