Title |
The combined effect of the T2DM susceptibility genes is an important risk factor for T2DM in non-obese Japanese: a population based case-control study
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Published in |
BMC Medical Genomics, February 2012
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DOI | 10.1186/1471-2350-13-11 |
Pubmed ID | |
Authors |
Kimiko Yamakawa-Kobayashi, Maki Natsume, Shingo Aoki, Sachi Nakano, Tomoko Inamori, Nobuhiko Kasezawa, Toshinao Goda |
Abstract |
Type 2 diabetes mellitus (T2DM) is a complex endocrine and metabolic disorder. Recently, several genome-wide association studies (GWAS) have identified many novel susceptibility loci for T2DM, and indicated that there are common genetic causes contributing to the susceptibility to T2DM in multiple populations worldwide. In addition, clinical and epidemiological studies have indicated that obesity is a major risk factor for T2DM. However, the prevalence of obesity varies among the various ethnic groups. We aimed to determine the combined effects of these susceptibility loci and obesity/overweight for development of T2DM in the Japanese. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Mexico | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 50% |
Scientists | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 28 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Professor > Associate Professor | 6 | 21% |
Student > Bachelor | 4 | 14% |
Student > Ph. D. Student | 3 | 11% |
Researcher | 3 | 11% |
Student > Master | 3 | 11% |
Other | 6 | 21% |
Unknown | 3 | 11% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 10 | 36% |
Medicine and Dentistry | 7 | 25% |
Biochemistry, Genetics and Molecular Biology | 2 | 7% |
Nursing and Health Professions | 2 | 7% |
Economics, Econometrics and Finance | 1 | 4% |
Other | 3 | 11% |
Unknown | 3 | 11% |