Performance assessment of variant calling pipelines using human whole exome sequencing and simulated data

Performance assessment of #variant calling pipelines using #human whole #exome #sequencing and simulated #data https://t.co/69PL9sRxDa

@MattOldach Here are a few papers: https://t.co/SF0MxlH0XR (this one also benchmarks novoalign) https://t.co/YcgDRxvjSa Blogs: https://t.co/KMtmFMzd1m https://t.co/yW9KiPtVqL The dv-cohort preprint also has benchmarks that include Mendelian violation:

Is it just me, or are most comparisons of GATK performance to alts skimpy on details? To get the most out of GATK you need to do realignment, base quality recalibration, joint genotyping with many samples done on the same platform... 1/2 #bioinformatics ht

RT @TheFirstNuomics: Performance assessment of variant calling pipelines using human whole exome sequencing and simulated data https://t.co…