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X Demographics
Mendeley readers
Attention Score in Context
| Title |
One-step of tryptophan attenuator inactivation and promoter swapping to improve the production of L-tryptophan in Escherichia coli
|
|---|---|
| Published in |
Microbial Cell Factories, March 2012
|
| DOI | 10.1186/1475-2859-11-30 |
| Pubmed ID | |
| Authors |
Pengfei Gu, Fan Yang, Junhua Kang, Qian Wang, Qingsheng Qi |
| Abstract |
L-tryptophan is an aromatic amino acid widely used in the food, chemical and pharmaceutical industries. In Escherichia coli, L-tryptophan is synthesized from phosphoenolpyruvate and erythrose 4-phosphate by enzymes in the shikimate pathway and L-tryptophan branch pathway, while L-serine and phosphoribosylpyrophosphate are also involved in L-tryptophan synthesis. In order to construct a microbial strain for efficient L-tryptophan production from glucose, we developed a one step tryptophan attenuator inactivation and promoter swapping strategy for metabolic flux optimization after a base strain was obtained by overexpressing the tktA, mutated trpE and aroG genes and inactivating a series of competitive steps. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Switzerland | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 86 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Australia | 1 | 1% |
| Mexico | 1 | 1% |
| Denmark | 1 | 1% |
| China | 1 | 1% |
| Spain | 1 | 1% |
| Unknown | 81 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 22 | 26% |
| Researcher | 16 | 19% |
| Student > Bachelor | 11 | 13% |
| Student > Master | 10 | 12% |
| Student > Doctoral Student | 5 | 6% |
| Other | 6 | 7% |
| Unknown | 16 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 33 | 38% |
| Biochemistry, Genetics and Molecular Biology | 17 | 20% |
| Engineering | 6 | 7% |
| Chemistry | 3 | 3% |
| Environmental Science | 2 | 2% |
| Other | 7 | 8% |
| Unknown | 18 | 21% |
Attention Score in Context
This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 October 2020.
All research outputs
#4,373,686
of 22,663,150 outputs
Outputs from Microbial Cell Factories
#223
of 1,581 outputs
Outputs of similar age
#26,876
of 156,014 outputs
Outputs of similar age from Microbial Cell Factories
#3
of 12 outputs
Altmetric has tracked 22,663,150 research outputs across all sources so far. Compared to these this one has done well and is in the 80th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,581 research outputs from this source. They receive a mean Attention Score of 4.4. This one has done well, scoring higher than 85% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 156,014 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 81% of its contemporaries.
We're also able to compare this research output to 12 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 75% of its contemporaries.