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Changes in coagulation functions and hemorheological parameters may predict hematoma formation after total knee arthroplasty

Overview of attention for article published in Journal of Orthopaedic Surgery and Research, March 2016
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Title
Changes in coagulation functions and hemorheological parameters may predict hematoma formation after total knee arthroplasty
Published in
Journal of Orthopaedic Surgery and Research, March 2016
DOI 10.1186/s13018-016-0370-5
Pubmed ID
Authors

Ning Liu, Simin Luo, Cheanglek Hang, Zhengang Zha, Jieruo Li, Wenrui Wu, Dabiao Hou

Abstract

Hematoma formation around the knee is commonly seen after total knee arthroplasty (TKA) and may cause patient discomfort and worry regarding the success of the surgery. This study aimed to evaluate the coagulation functions and hemorheological parameters in patients undergoing TKA and investigate their associations with hematoma formation. This study prospectively included 146 patients treated for knee osteoarthritis by unilateral TKA between August 2013 and August 2014. Apixaban was administered twice during the 12-24-h period after surgery. Blood coagulation functions were evaluated according to activated partial thromboplastin time (APTT), prothrombin time (PT), thrombin time, and fibrinogen preoperatively and on postoperative days 1, 3, 7, and 14. Hemorheological parameters were also measured. Patients were divided into a hematoma group and a non-hematoma group for comparison. On postoperative day 1, the hematoma group showed significantly prolonged APTT and PT and significantly decreased hematocrit relative to baseline values (P < 0.05). The whole blood high shear rate, whole blood low shear rate, plasma viscosity, and hematocrit did not differ significantly between the two groups at baseline or from postoperative days 1-14 in (P > 0.05). Prolonged APTT and PT on the first day after TKA as well as decreased hematocrit may indicate an increased risk of hematoma formation. Postoperative use of apixaban may promote the formation of ecchymoses but is not a major contributing factor.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 32 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Slovenia 1 3%
Unknown 31 97%

Demographic breakdown

Readers by professional status Count As %
Student > Master 4 13%
Student > Bachelor 4 13%
Student > Doctoral Student 3 9%
Student > Ph. D. Student 3 9%
Researcher 2 6%
Other 5 16%
Unknown 11 34%
Readers by discipline Count As %
Medicine and Dentistry 12 38%
Pharmacology, Toxicology and Pharmaceutical Science 3 9%
Nursing and Health Professions 2 6%
Unspecified 1 3%
Business, Management and Accounting 1 3%
Other 2 6%
Unknown 11 34%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 April 2016.
All research outputs
#14,255,539
of 22,858,915 outputs
Outputs from Journal of Orthopaedic Surgery and Research
#495
of 1,374 outputs
Outputs of similar age
#160,137
of 300,491 outputs
Outputs of similar age from Journal of Orthopaedic Surgery and Research
#12
of 32 outputs
Altmetric has tracked 22,858,915 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,374 research outputs from this source. They receive a mean Attention Score of 3.6. This one has gotten more attention than average, scoring higher than 58% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 300,491 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 43rd percentile – i.e., 43% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 32 others from the same source and published within six weeks on either side of this one. This one is in the 43rd percentile – i.e., 43% of its contemporaries scored the same or lower than it.